BDBM475730 1-[(3aR,3bS,6aR,6bS)-5-(1H- benzotriazole-5-carbonyl)-octahydro- cyclobuta[1,2-c;3,4-c']dipyrrol-2-yl]-2-(2- isopropyl-phenoxy)-ethanone::US10849881, Example 1.009

SMILES CC(C)c1ccccc1OCC(=O)N1C[C@H]2[C@@H](C1)[C@@H]1CN(C[C@H]21)C(=O)c1ccc2[nH]nnc2c1

InChI Key InChIKey=USLNSMSYKNTRSA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475730   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM475730(1-[(3aR,3bS,6aR,6bS)-5-(1H- benzotriazole-5-carbon...)
Affinity DataIC50: 8nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
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Date in BDB:
7/13/2021
Entry Details
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