BDBM476545 (8-endo)-3-(3-methyl-1,2,4-oxadiazol-5-yl)-3-azabicyclo[3.2.1]octan-8-amine::US10875854, Example 18

SMILES Cc1noc(N2C[C@H]3CC[C@@H](C2)[C@@H]3Nc2nc3c(C(C)C)ccc(OCC(F)(F)F)n3n2)n1

InChI Key InChIKey=ISRJHXZPHXHVPI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476545   

LigandChemical structure of BindingDB Monomer ID 476545BDBM476545(US10875854, Example 18 | (8-endo)-3-(3-methyl-1,2,...)
Affinity DataEC50:  37.4nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2021
Entry Details
US Patent