BDBM476666 (S)-6-(3-Fluoro-8-(prop-1-yn-1-yl) dibenzo[b,d]thiophen-2-yl)-2-imino-3,6- dimethyltetrahydropyrimidin-4(1H)-one::US10870635, Example 72

SMILES CC#Cc1ccc2sc3cc(F)c(cc3c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1

InChI Key InChIKey=YMLPCTFQURLHKJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476666   

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476666(US10870635, Example 72 | (S)-6-(3-Fluoro-8-(prop-1...)
Affinity DataIC50: 21nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent