BDBM476673 (6S)-2-Imino-3,6-dimethyl-6-(5-oxido-8- (prop-1-yn-1-yl)dibenzo[b,d]thiophen- 2-yl)tetrahydropyrimidin-4(1H)-one::US10870635, Example 80

SMILES CC#Cc1ccc2c(c1)c1cc(ccc1s2=O)[C@]1(C)CC(=O)N(C)C(=N)N1

InChI Key InChIKey=JHTRHPZKVVJSMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476673   

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476673(US10870635, Example 80 | (6S)-2-Imino-3,6-dimethyl...)
Affinity DataIC50: 48nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent