BDBM476679 (S)-6-(8-(3-Hydroxyprop-1-yn-1-yl) dibenzo[b,d]thiophen-2-yl)-2-imino-3,6- dimethyltetrahydropyrimidin-4(1H)- one::US10870635, Example 87

SMILES CN1C(=N)N[C@@](C)(CC1=O)c1ccc2sc3ccc(cc3c2c1)C#CCO

InChI Key InChIKey=MTGMTYUQCPYYMZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476679   

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476679(US10870635, Example 87 | (S)-6-(8-(3-Hydroxyprop-1...)
Affinity DataIC50: 17nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent