BDBM476683 (S)-8-(2-Imino-1,4-dimethyl-6- oxohexahydropyrimidin-4-yl)dibenzo [b,d]thiophene-2-carboxamide::US10870635, Example 91

SMILES CN1C(=N)N[C@@](C)(CC1=O)c1ccc2sc3ccc(cc3c2c1)C(N)=O

InChI Key InChIKey=ROBXYRZNCQLYQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476683   

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476683(US10870635, Example 91 | (S)-8-(2-Imino-1,4-dimeth...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent