BDBM476687 (R)-5,5-Difluoro-4-methyl-4-(8-(prop- 1-yn-1-yl)dibenzo[b,d]thiophen-2-yl)- 1,3-oxazinan-2-imine::US10870635, Example 100

SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@@]1(C)NC(=N)OCC1(F)F

InChI Key InChIKey=YZFSPSBGKUKIIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476687   

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476687(US10870635, Example 100 | (R)-5,5-Difluoro-4-methy...)
Affinity DataIC50: 202nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent