BDBM476689 (R)-3-Imino-2,5-dimethyl-5-(8-(prop- 1-yn-1-yl)dibenzo[b,d]thiophen-2-yl)- 1,2,4-thiadiazinane 1,1-dioxide::US10870635, Example 104

SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@]1(C)CS(=O)(=O)N(C)C(=N)N1

InChI Key InChIKey=IHSBXFYIRGZLBH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476689   

TargetBeta-secretase 1(Human)
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476689(US10870635, Example 104 | (R)-3-Imino-2,5-dimethyl...)
Affinity DataIC50: 300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
US Patent