BDBM477079 4-(5-(trifluoromethyl)-4-((2- (trifluoromethyl)pyridin-4- yl)carbamoyl)-1H-pyrazol-1- yl)pyrazolo[1,5-a]pyridine-7- carboxamide::US10888550, Compound 12

SMILES NC(=O)c1ccc(-n2ncc(C(=O)Nc3ccnc(c3)C(F)(F)F)c2C(F)(F)F)c2ccnn12

InChI Key InChIKey=YLAHPJCNVZCUNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477079   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM477079(US10888550, Compound 12 | 4-(5-(trifluoromethyl)-4...)
Affinity DataIC50: 219nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2021
Entry Details
US Patent