BDBM477194 US10889546, Example 4

SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CC1CC1

InChI Key InChIKey=AEYLHGBTQFPILZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477194   

TargetEgl nine homolog 1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477194(US10889546, Example 4)
Affinity DataIC50: 835nMAssay Description:The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
Go to US Patent

TargetEgl nine homolog 1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477194(US10889546, Example 4)
Affinity DataIC50: 835nMAssay Description:Inhibition of FITC-HIF1alpha (556 to 574 residues) binding to PHD2 (181 to 426 residues) (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed