BDBM477635 6-Fluoro-3-(1-(5-(methoxymethyl)-4-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl) azetidin-3-yl)-1-methyl-1H-indole 14::US10889569, Example 14

SMILES COCc1nnc(N2CC(C2)c2cn(C)c3cc(F)ccc23)n1-c1ccc(OC)nc1

InChI Key InChIKey=UVZWJORSNJBCBT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 477635   

TargetVasopressin V1a receptor(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477635(US10889569, Example 14 | 6-Fluoro-3-(1-(5-(methoxy...)
Affinity DataIC50: 1.09E+4nMAssay Description:V1aR: The inhibition effect of the compounds of the present invention on the activity of human V1 aR protein expressed in HEK293/human V1aR stably tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetVasopressin V2 receptor(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477635(US10889569, Example 14 | 6-Fluoro-3-(1-(5-(methoxy...)
Affinity DataIC50: 1.18E+4nMAssay Description:V2R: The inhibition effect of the compounds of the present invention on the activity of human V2R protein expressed in HEK293/human V2R cells was det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477635(US10889569, Example 14 | 6-Fluoro-3-(1-(5-(methoxy...)
Affinity DataIC50: 2.58E+4nMAssay Description:V1bR: The inhibition effect of the compounds of the present invention on the activity of human V1bR protein expressed in HEK293/human V1bR cells was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent