BDBM477640 5-(3-(3-(7-Fluorobenzodihydropyran-4-yl)azetidin-1-yl)-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine 21::US10889569, Example 21

SMILES COCc1nnc(N2CC(C2)C2CCOc3cc(F)ccc23)n1-c1ccc(OC)nc1

InChI Key InChIKey=QPGASICOOIKEGG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 477640   

TargetVasopressin V1a receptor(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477640(US10889569, Example 21 | 5-(3-(3-(7-Fluorobenzodih...)
Affinity DataIC50: 2.70E+3nMAssay Description:V1aR: The inhibition effect of the compounds of the present invention on the activity of human V1 aR protein expressed in HEK293/human V1aR stably tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetVasopressin V2 receptor(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477640(US10889569, Example 21 | 5-(3-(3-(7-Fluorobenzodih...)
Affinity DataIC50: 1.73E+4nMAssay Description:V2R: The inhibition effect of the compounds of the present invention on the activity of human V2R protein expressed in HEK293/human V2R cells was det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetVasopressin V1b receptor(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477640(US10889569, Example 21 | 5-(3-(3-(7-Fluorobenzodih...)
Affinity DataIC50: 3.88E+4nMAssay Description:V1bR: The inhibition effect of the compounds of the present invention on the activity of human V1bR protein expressed in HEK293/human V1bR cells was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent