BDBM477650 4-(1-(5-(Difluoromethyl)-4-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl)azetidin-3-yl)-7-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine 35::US10889569, Example 35

SMILES COc1ccc(cn1)-n1c(nnc1N1CC(C1)N1CCOc2cc(F)ccc12)C(F)F

InChI Key InChIKey=WGYPISTWZSDWKR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477650   

TargetVasopressin V1a receptor(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477650(US10889569, Example 35 | 4-(1-(5-(Difluoromethyl)-...)
Affinity DataIC50: 1.41E+4nMAssay Description:V1aR: The inhibition effect of the compounds of the present invention on the activity of human V1 aR protein expressed in HEK293/human V1aR stably tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent