BDBM477657 7-Fluoro-4-(1-(4-(6-methoxypyridin-3-yl)-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl) azetidin-3-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine 43::US10889569, Example 43

SMILES COc1ccc(cn1)-n1c(nnc1C(F)(F)F)N1CC(C1)N1CCOc2cc(F)ccc12

InChI Key InChIKey=COFWLMVAHSRFSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477657   

TargetVasopressin V1a receptor(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477657(US10889569, Example 43 | 7-Fluoro-4-(1-(4-(6-metho...)
Affinity DataIC50: 7.90E+3nMAssay Description:V1aR: The inhibition effect of the compounds of the present invention on the activity of human V1 aR protein expressed in HEK293/human V1aR stably tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent