BDBM477661 US10889571, Example 2

SMILES O[C@H]1CC(C1)n1cnc2cc(cc(-c3cncnc3)c12)C(=O)Nc1ccc(OC(F)(F)Cl)cc1

InChI Key InChIKey=DRLGQKRSNKZMSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477661   

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Terns

US Patent
LigandPNGBDBM477661(US10889571, Example 2)
Affinity DataIC50: 0.370nMAssay Description:ABL1 WT protein (64-515aa) containing an N-terminal His tag was produced by co-expression with YopH in Sf9 insect cells. Cells were harvested by cent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent