BDBM478126 US10894052, Example 21::US10894052, Example 22::cyclopropyl(methyl)((4-((R)-3- methylmorpholino)-6-(1H- pyrrolo[2,3-c]pyridin-4-yl)pyridin-2- yl)imino)-lambda6-sulfanone

SMILES C[C@@H]1COCCN1c1cc(N=S(C)(=O)C2CC2)nc(c1)-c1cncc2[nH]ccc12

InChI Key InChIKey=JRFXASXSFNWUCN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478126   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM478126(US10894052, Example 21 | cyclopropyl(methyl)((4-((...)
Affinity DataIC50: 6nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM478126(US10894052, Example 21 | cyclopropyl(methyl)((4-((...)
Affinity DataIC50: 9nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent