BDBM478138 1-({6-[(3R)-3-methylmorpholin-4-yl]- 2-{1H-pyrrolo[2,3-b]pyridin-4- yl}pyrimidin-4-yl}imino)-lambda6-thian-1- one::US10894052, Example 30

SMILES C[C@@H]1COCCN1c1cc(N=S2(=O)CCOCC2)nc(c1)-c1ccnc2[nH]ccc12

InChI Key InChIKey=ZGQANAOWJYMOJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478138   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
University Of Texas

US Patent
LigandPNGBDBM478138(1-({6-[(3R)-3-methylmorpholin-4-yl]- 2-{1H-pyrrolo...)
Affinity DataIC50: 8nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
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Date in BDB:
8/14/2021
Entry Details
US Patent