BDBM478621 US10894784, Example 86.03::cyclopropyl{4-[(1R or 1S)-1-(2-{[6-(1-{[(1RS)-2,2-difluorocyclopropyl]methyl}-1H-pyrazol-4-yl)-7-fluoro-1H-benzimidazol-2-yl]amino}pyridin-4-yl)ethyl]piperazin-1-yl}methanone

SMILES CC(N1CCN(CC1)C(=O)C1CC1)c1ccnc(Nc2nc3ccc(-c4cnn(CC5CC5(F)F)c4)c(F)c3[nH]2)c1

InChI Key InChIKey=SGYGPXUCVDWKPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478621   

TargetSerine/threonine-protein kinase TBK1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM478621(US10894784, Example 86.03 | cyclopropyl{4-[(1R or ...)
Affinity DataIC50: 1.5nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent