BDBM479156 US10894789, Compound 177

SMILES COc1ccc(cc1)-c1cn(C)nc1C(=O)N1CC(F)(F)C[C@@H](C)C1CNc1ccc(cn1)C(F)(F)F

InChI Key InChIKey=BKUZWOSERQDQAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 479156   

TargetOrexin/Hypocretin receptor type 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM479156(US10894789, Compound 177)
Affinity DataIC50: 6nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Astrazeneca

US Patent
LigandPNGBDBM479156(US10894789, Compound 177)
Affinity DataIC50: 170nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details
US Patent