BDBM479486 ML300-based SC inhibitor 25::US20240239772, Compound 25

SMILES O=C(Cn1nnc2ccccc12)N(CC1CCCC1)c1ccc(cc1)-c1cccnc1

InChI Key InChIKey=MUXXBMHXURKPHX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 479486   

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM479486(ML300-based SC inhibitor 25 | US20240239772, Compo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM479486(ML300-based SC inhibitor 25 | US20240239772, Compo...)
Affinity DataIC50: 1.00E+3nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM479486(ML300-based SC inhibitor 25 | US20240239772, Compo...)
Affinity DataIC50: 1.16E+3nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM479486(ML300-based SC inhibitor 25 | US20240239772, Compo...)
Affinity DataIC50: 1.16E+3nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed