BDBM479495 ML300-based SC inhibitor 34::US20240239772, Compound 34

SMILES Clc1cncc(CN(C(=O)Cn2nnc3ccccc23)c2ccc(cc2)-c2cccnc2)c1

InChI Key InChIKey=AZRNSMNPERAERM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 479495   

TargetReplicase polyprotein 1ab(SARS-CoV)
Cleveland Clinic

LigandPNGBDBM479495(ML300-based SC inhibitor 34 | US20240239772, Compo...)
Affinity DataIC50: 370nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cleveland Clinic

LigandPNGBDBM479495(ML300-based SC inhibitor 34 | US20240239772, Compo...)
Affinity DataIC50: 540nMAssay Description:The protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, end point assay adapted from a previ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Cleveland Clinic

LigandPNGBDBM479495(ML300-based SC inhibitor 34 | US20240239772, Compo...)
Affinity DataIC50: 370nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Cleveland Clinic

LigandPNGBDBM479495(ML300-based SC inhibitor 34 | US20240239772, Compo...)
Affinity DataIC50: 540nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent