BDBM4804 (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}-N'-[3-(morpholin-4-yl)propyl]but-2-enediamide::(2E)-N1-[4-(3-Chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]-N4-[3-(4-morpholinyl)propyl]-2-butenediamide::4-Anilinopyrido[3,4-d]pyrimidine 31

SMILES Fc1ccc(Nc2ncnc3cnc(NC(=O)\C=C\C(=O)NCCCN4CCOCC4)cc23)cc1Cl

InChI Key InChIKey=KNXXEFGLJICDBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4804   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4804((2E)-N1-[4-(3-Chloro-4-fluoroanilino)pyrido[3,4-d]...)
Affinity DataIC50: 0.610nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed