BDBM480494 N-(3-(4-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)piperidin-1-yl)phenyl)acetamide trifluoroacetate::US10899764, Example 12

SMILES CC(=O)Nc1cccc(c1)N1CCC(CC1)C1c2c(cccc2F)-c2cncn12

InChI Key InChIKey=DRXODMGXZPHONE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480494   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM480494(N-(3-(4-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)p...)
Affinity DataIC50: 68.7nMAssay Description:IDO1: For testing, 24 μL of enzyme (IDO1) was diluted 100 times with 50 mM KPB to 2400 μL. The concentration of the enzyme solution was 2.6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent