BDBM480512 6-fluoro-5-(1-(5-((1-(methylsulfonyl)piperidin-3-yl)oxy)pyrimidin-2-yl)piperidin-4-yl)-5H-imidazo[5,1-a]isoindole trifluoroacetate::US10899764, Example 37

SMILES CS(=O)(=O)N1CCCC(C1)Oc1cnc(nc1)N1CCC(CC1)C1c2c(cccc2F)-c2cncn12

InChI Key InChIKey=MDZMBVVAYUZUNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480512   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM480512(6-fluoro-5-(1-(5-((1-(methylsulfonyl)piperidin-3-y...)
Affinity DataIC50: 17.8nMAssay Description:IDO1: For testing, 24 μL of enzyme (IDO1) was diluted 100 times with 50 mM KPB to 2400 μL. The concentration of the enzyme solution was 2.6...More data for this Ligand-Target Pair
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Date in BDB:
8/15/2021
Entry Details
US Patent