BDBM480746 N-(2,2-dimethyl-6-morpholino- 3H-benzofuran-5-yl)-1-[2-(2,2,2- trifluoroethylamino)-4- pyridyl]pyrazole-3-carboxamide::US10899774, Example 62

SMILES CC1(C)Cc2cc(NC(=O)c3ccn(n3)-c3ccnc(NCC(F)(F)F)c3)c(cc2O1)N1CCOCC1

InChI Key InChIKey=MDYYTPLWTFBBHI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480746   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM480746(US10899774, Example 62 | N-(2,2-dimethyl-6-morphol...)
Affinity DataKi:  17nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2021
Entry Details
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