BDBM481046 US10906890, Example 58.0::US10906890, Example 59.0

SMILES COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@H]2C[C@H](CN(C2)c2ncc(F)cn2)OC(C)C)nnc1-c1ccccc1

InChI Key InChIKey=ILXJWZBRDGKKDE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 481046   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM481046(US10906890, Example 59.0 | US10906890, Example 58....)
Affinity DataEC50:  0.940nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM481046(US10906890, Example 59.0 | US10906890, Example 58....)
Affinity DataEC50:  86nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
US Patent