BDBM481156 US10906900, Reference 22d

SMILES CN(C)c1ccc(cc1)C#Cc1cc2cnccc2[nH]1

InChI Key InChIKey=KVNVGAUWCHPHOE-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 481156   

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481156(US10906900, Reference 22d)
Affinity DataKd:  3.60nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent

TargetAlpha-synuclein(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481156(US10906900, Reference 22d)
Affinity DataKd:  1nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent

TargetIsoform Tau-F of Microtubule-associated protein tau(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481156(US10906900, Reference 22d)
Affinity DataKd:  2.40nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent

TargetAlpha-synuclein(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481156(US10906900, Reference 22d)
Affinity DataKd:  1nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent