BDBM481157 US10906900, Reference 25a

SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(nc2[nH]1)-c1cccs1

InChI Key InChIKey=CSWYTFLVWXTIPC-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 481157   

TargetAmyloid-beta precursor protein [1-42](Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481157(US10906900, Reference 25a)
Affinity DataKd:  4.90nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent

TargetAlpha-synuclein(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481157(US10906900, Reference 25a)
Affinity DataKd:  0.490nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent

TargetIsoform Tau-F of Microtubule-associated protein tau(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481157(US10906900, Reference 25a)
Affinity DataKd:  1.67nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent

TargetAlpha-synuclein(Human)
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481157(US10906900, Reference 25a)
Affinity DataKd:  0.490nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2021
Entry Details
Go to US Patent