BDBM481780 1-([4-[2-(4- chlorophenyl)ethyl]-5-oxo- 4,5-dihydro-1,3,4-oxadiazol- 2-yl]methyl)-6-methyl-7-oxo- 1H,6H,7H-pyrazolo[4,3- d]pyrimidine-3-carbonitrile::US10913742, Example 22

SMILES Cn1cnc2c(nn(Cc3nn(CCc4ccc(Cl)cc4)c(=O)o3)c2c1=O)C#N

InChI Key InChIKey=ZJLYAVZPZQXDIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481780   

LigandPNGBDBM481780(1-([4-[2-(4- chlorophenyl)ethyl]-5-oxo- 4,5-dihydr...)
Affinity DataIC50: 14nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent