BDBM481792 5-[(5-methyl-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)methyl]-3- [(2S)-2-(4-chlorophenyl)-2- fluoro-ethyl]-1,3,4-oxadiazol- 2-one::US10913742, Example 34

SMILES Cc1ccnc2ncn(Cc3nn(C[C@H](F)c4ccc(Cl)cc4)c(=O)o3)c(=O)c12

InChI Key InChIKey=LGDQCKVOXHGGTO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481792   

LigandPNGBDBM481792(5-[(5-methyl-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)me...)
Affinity DataIC50: 5nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent