BDBM481818 3-[[4-[3-fluoro-3-(4- fluorophenyl)cyclobutyl]-5- oxo-1,3,4-oxadiazol-2- yl]methyl]-5-methyl-4-oxo- pyrido[2,3-d]pyrimidine-7- carbonitrile::US10913742, Example 61

SMILES Cc1cc(nc2ncn(Cc3nn([C@H]4C[C@@](F)(C4)c4ccc(F)cc4)c(=O)o3)c(=O)c12)C#N

InChI Key InChIKey=OXBAGLABLAJOLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481818   

LigandPNGBDBM481818(3-[[4-[3-fluoro-3-(4- fluorophenyl)cyclobutyl]-5- ...)
Affinity DataIC50: 11.2nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
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Date in BDB:
8/30/2021
Entry Details
US Patent