BDBM481822 US10913742, Example 65::trans-2-[[4-[3-(4- chlorophenyl)cyclobutyl]-5- oxo-1,3,4-oxadiazol-2- yl]methyl]pyrido[1,2- a]pyrazine-1,6-dione

SMILES Clc1ccc(cc1)[C@H]1C[C@@H](C1)n1nc(Cn2ccn3c(cccc3=O)c2=O)oc1=O

InChI Key InChIKey=LNHYIPIWVZDRTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481822   

LigandPNGBDBM481822(trans-2-[[4-[3-(4- chlorophenyl)cyclobutyl]-5- oxo...)
Affinity DataIC50: 21.1nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent