BDBM481827 US10913742, Example 70::trans-3-[3-(3- chlorophenoxy)cyclobutyl]- 5-[(7-methyl-6-oxo-purin-1- yl)methyl]-1,3,4-oxadiazol- 2-one

SMILES Cn1cnc2ncn(Cc3nn([C@H]4C[C@@H](C4)Oc4cccc(Cl)c4)c(=O)o3)c(=O)c12

InChI Key InChIKey=ZXZGHARNRVRJPP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481827   

LigandPNGBDBM481827(trans-3-[3-(3- chlorophenoxy)cyclobutyl]- 5-[(7-me...)
Affinity DataIC50: 17.7nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent