BDBM481829 5-[(5-chloro-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)methyl]-3-[3- (4-chlorophenyl)cyclobutyl]- 1,3,4-oxadiazol-2-one::US10913742, Example 73

SMILES Clc1ccc(cc1)[C@H]1C[C@@H](C1)n1nc(Cn2cnc3nccc(Cl)c3c2=O)oc1=O

InChI Key InChIKey=VMPWGDIXDVYPGX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481829   

LigandPNGBDBM481829(5-[(5-chloro-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)me...)
Affinity DataIC50: 5.88nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent