BDBM481831 3-[3-fluoro-3-(3- fluorophenyl)cyclobutyl]-5- [(5-methyl-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)methyl]-1,3,4- oxadiazol-2-one::US10913742, Example 75

SMILES Cc1ccnc2ncn(Cc3nn([C@H]4C[C@@](F)(C4)c4cccc(F)c4)c(=O)o3)c(=O)c12

InChI Key InChIKey=CZSWXNBPJXPCFZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481831   

LigandPNGBDBM481831(3-[3-fluoro-3-(3- fluorophenyl)cyclobutyl]-5- [(5-...)
Affinity DataIC50: 40.5nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent