BDBM481839 3-((4-((trans)-3-(4- chlorophenyl)cyclobutyl)-5- oxo-4,5-dihydro-1,3,4- oxadiazol-2-yl)methyl)-5- methylpyrido[3,2-d]pyrimidine- 4,6(3H,5H)-dione::US10913742, Example 83

SMILES Cn1c2c(ccc1=O)ncn(Cc1nn([C@H]3C[C@@H](C3)c3ccc(Cl)cc3)c(=O)o1)c2=O

InChI Key InChIKey=JOVMFRRSFHVPLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481839   

LigandPNGBDBM481839(3-((4-((trans)-3-(4- chlorophenyl)cyclobutyl)-5- o...)
Affinity DataIC50: 15.2nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent