BDBM481842 1-([4-[3-(3- chlorophenoxy)propyl]-5- oxo-4,5-dihydro-1,3,4- oxadiazol-2-yl]methyl)-7- methyl-6,7-dihydro-1H- purin-6-one::US10913742, Example 86

SMILES Cn1cnc2ncn(Cc3nn(CCCOc4cccc(Cl)c4)c(=O)o3)c(=O)c12

InChI Key InChIKey=LFVOFPFXYXXTEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481842   

LigandPNGBDBM481842(1-([4-[3-(3- chlorophenoxy)propyl]-5- oxo-4,5-dihy...)
Affinity DataIC50: 22.6nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent