BDBM481859 3-[3-(4-chlorophenyl)-3- fluoro-cyclobutyl]-5-[(5- methyl-4-oxo-pyrido[2,3- d]pyrimidin-3-yl)methyl]- 1,3,4-oxadiazol-2-one::US10913742, Example 104

SMILES Cc1ccnc2ncn(Cc3nn([C@H]4C[C@@](F)(C4)c4ccc(Cl)cc4)c(=O)o3)c(=O)c12

InChI Key InChIKey=AOZCJXPKMNJCQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481859   

LigandPNGBDBM481859(3-[3-(4-chlorophenyl)-3- fluoro-cyclobutyl]-5-[(5-...)
Affinity DataIC50: 29.6nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent