BDBM481864 5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[rac-(2R)-2- fluoro-2-[4- (trifluoromethoxy)phenyl]ethyl]- 1,3,4-oxadiazol-2-one::US10913742, Example 109

SMILES Cn1cnc2ncn(Cc3nn(C[C@H](F)c4ccc(OC(F)(F)F)cc4)c(=O)o3)c(=O)c12

InChI Key InChIKey=CRMCPZOEWQJMFS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481864   

LigandPNGBDBM481864(5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[rac-(2R)...)
Affinity DataIC50: 19.1nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent