BDBM481868 5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[3-(2- naphthyl)cyclobutyl]-1,3,4- oxadiazol-2-one::US10913742, Example 113

SMILES Cn1cnc2ncn(Cc3nn([C@H]4C[C@@H](C4)c4ccc5ccccc5c4)c(=O)o3)c(=O)c12

InChI Key InChIKey=CANXPAGDHYDXAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481868   

LigandPNGBDBM481868(5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[3-(2- na...)
Affinity DataIC50: 17.8nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent