BDBM481918 (3aR,6aS)-3,5-Dichlorobenzyl 5-(5-(methylsulfonamido)picolinoyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate::US10913745, Example 6

SMILES CS(=O)(=O)Nc1ccc(nc1)C(=O)N1C[C@@H]2CN(C[C@@H]2C1)C(=O)OCc1cc(Cl)cc(Cl)c1

InChI Key InChIKey=FGSJKFLDXHNAOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481918   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM481918(US10913745, Example 6 | (3aR,6aS)-3,5-Dichlorobenz...)
Affinity DataIC50: 622nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
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