BDBM483870 1-(5-(2,5- dichlorobenzyl)- octahydropyrrolo- [3,4-c]pyrrole-2- carbonyl)-N-methyl- 1H-pyrazole-3- carboxamide::US10927105, Ex 430::US11655217, Example 430

SMILES CNC(=O)c1ccn(n1)C(=O)N1CC2CN(Cc3cc(Cl)ccc3Cl)CC2C1

InChI Key InChIKey=JXNXXUYMEJCETA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483870   

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483870(US10927105, Ex 430 | 1-(5-(2,5- dichlorobenzyl)- o...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483870(US10927105, Ex 430 | 1-(5-(2,5- dichlorobenzyl)- o...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent