BDBM483887 1-(trans-5-(2- chloro-3-(2- hydroxy-2- methylpropoxy)- phenoxy)- octahydrocyclopenta- [c]pyrrole-2- carbonyl)-1H- pyrazole-3- carboxylic acid::US10927105, Ex 451::US11655217, Example 451

SMILES CC(C)(O)COc1cccc(O[C@@H]2C[C@H]3CN(C[C@H]3C2)C(=O)n2ccc(n2)C(O)=O)c1Cl

InChI Key InChIKey=AFVYBQAUZVFZHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483887   

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483887(US10927105, Ex 451 | 1-(trans-5-(2- chloro-3-(2- h...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2021
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Lundbeck La Jolla Research Center

US Patent
LigandPNGBDBM483887(US10927105, Ex 451 | 1-(trans-5-(2- chloro-3-(2- h...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
US Patent