BDBM484281 (S)-1-(2-(1-(4-(2-fluoro-3- methoxyphenoxy)phenyl)-5,8- dimethylimidazo[1,5-a]pyrazin-3- yl)piperidin-1-yl)prop-2-en-1-one::US10933063, Compound 80::US11554118, Compound 80

SMILES COc1cccc(Oc2ccc(cc2)-c2nc([C@@H]3CCCCN3C(=O)C=C)n3c(C)cnc(C)c23)c1F

InChI Key InChIKey=YDWAXCKDAWKUKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484281   

TargetTyrosine-protein kinase BTK(Human)
Suzhou Baijibugong Pharmaceutical Technology

US Patent
LigandPNGBDBM484281((S)-1-(2-(1-(4-(2-fluoro-3- methoxyphenoxy)phenyl)...)
Affinity DataIC50: 55nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details Article
US Patent

TargetTyrosine-protein kinase BTK(Human)
Suzhou Baijibugong Pharmaceutical Technology

US Patent
LigandPNGBDBM484281((S)-1-(2-(1-(4-(2-fluoro-3- methoxyphenoxy)phenyl)...)
Affinity DataIC50: 55nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2021
Entry Details
US Patent