BDBM485703 N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(3-methanesulfonylbenzyloxy) benzyl) pipecolinic acid::US10941129, Example 28

SMILES CS(=O)(=O)c1cccc(COc2cc(OCc3cccc(c3Br)-c3ccccc3)c(Cl)cc2CN2CCCC[C@H]2C(O)=O)c1

InChI Key InChIKey=WHWBOXLOCRUZPU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 485703   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM485703(N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(3-met...)
Affinity DataIC50: 10nMAssay Description:1) Principle: PD-1 protein is with HIS tag, and PD-1 ligand PD-L1 is with hFc tag. Eu labeled anti-hFc antibody and XL665 labeled anti-HIS antibody a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
US Patent