BDBM485872 US10946019, Example 20

SMILES C\C=C\c1c(Nc2ccc(cc2)C(O)=O)nc(nc1C(F)(F)F)-c1ccc(Cl)cc1

InChI Key InChIKey=JZCRYBLEESHBDC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 485872   

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandPNGBDBM485872(US10946019, Example 20)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent