BDBM487169 3-(3-(2-chloro-3-ethyl-1H- pyrrolo[2,3-b]pyridin-5- yl)phenyl)piperazin-2-one::US10952995, Compound 1-25

SMILES CCc1c(Cl)[nH]c2ncc(cc12)-c1cccc(c1)C1NCCNC1=O

InChI Key InChIKey=RPBRUBXFFAQDMC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487169   

LigandPNGBDBM487169(3-(3-(2-chloro-3-ethyl-1H- pyrrolo[2,3-b]pyridin-5...)
Affinity DataKi:  31nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent