BDBM487171 6-amino-3-(2-chloro-3-ethyl- 1H-pyrrolo[2,3-b]pyridin-5-yl)- 2-fluoro-N,N- dimethylbenzamide::US10952995, Compound 1-27

SMILES CCc1c(Cl)[nH]c2ncc(cc12)-c1ccc(N)c(C(=O)N(C)C)c1F

InChI Key InChIKey=QEZUQGHVFWJIKD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487171   

LigandPNGBDBM487171(6-amino-3-(2-chloro-3-ethyl- 1H-pyrrolo[2,3-b]pyri...)
Affinity DataKi:  2.70nMAssay Description:The presently disclosed compounds find use in inhibiting the activity of the enzyme HPK1. HPK1, also referred to as mitogen activated protein kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent