BDBM487933 US10954214, Compound 355::methyl 3-chloro-5-(1-(1-oxo-1,2- dihydroisoquinolin-5-yl)-5- (trifluoromethyl)-1H-pyrazole-4- carboxamido)picolinate

SMILES COC(=O)c1ncc(NC(=O)c2cnn(c2C(F)(F)F)-c2cccc3c2cc[nH]c3=O)cc1Cl

InChI Key InChIKey=WBGQQCPDPWJUTH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 487933   

TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487933(methyl 3-chloro-5-(1-(1-oxo-1,2- dihydroisoquinoli...)
Affinity DataIC50: 10nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
Go to US Patent