BDBM490056 (S)-N-(3-([1,1'-biphenyl]-4-yl)-1- ((4-(N-(tert- butyl)sulfamoyl)phenyl)amino)-1- oxopropan-2-yl)-4- fluorobenzamide::US10968172, ID # 19l

SMILES CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)[C@H](Cc2ccc(cc2)-c2ccccc2)NC(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=AYEULFQMTRIJKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 490056   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mitobridge

US Patent
LigandPNGBDBM490056(US10968172, ID # 19l | (S)-N-(3-([1,1'-biphenyl]-4...)
Affinity DataIC50: 169nMAssay Description:The in vitro assay for USP30 evaluates the ability of a test compound to inhibit the activity of the enzyme to cleave ubiquitin from a substrate. Ubi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mitobridge

US Patent
LigandPNGBDBM490056(US10968172, ID # 19l | (S)-N-(3-([1,1'-biphenyl]-4...)
Affinity DataIC50: 525nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent